Progesterone's inhibitory effects on smooth muscle influences that need to urinate. Later in pregnancy, urinary frequency will be an issue as the uterus compresses the bladder and therefore reduces capacity. Many women will get up more than once during the night to relieve themselves, and this interrupts valuable sleep time.
Although it has long been called "morning sickness," many expecting mothers will clarify that nausea in the first trimester can (and will) happen at any time. Meir H. Kryger, M.D., author of A Woman's Guide to Sleep Disorders explains,
"Morning sickness, which is quite common in the first twelve weeks of pregnancy, can also cause women to awaken with nausea, sometimes before they are ready to wake up."
First Trimester Survival Tips