of falls. Orexins work on a targeted chemical system—one that is mainly involved in arousal. The hope is that they will cause fewer side effects than other sleep aids on the market.
Some researchers are encouraged by the information known so far about this new class of sleep aid. However, additional clinical studies are needed to understand more about orexins, as they may have side effects of their own. Researchers are continuing to study these medications to find out if they cause next day drowsiness or mood changes, as well as how they change “sleep architecture” (the structure and pattern of sleep); for example, orexins may change the amount of REM sleep a person gets.