promising early results. However, the materials used were not adequately strong/durable to withstand steady tongue movement with breakage of prongs and slippage of tethers. Thus further engineering of such devices will be required before they are likely to be successful. However, the concept seems to be sound.
Pharmacologic approaches to apnea therapy : Over the years many trials of various pharmacologic agents have been attempted in OSA patients with limited to no success. There are not, at this time, any visible such trials ongoing or active work by pharmaceutical companies to develop a drug for the treatment of OSA. However, this could change quickly as our understanding of the neurobiology of the brainstem control of the pharyngeal musculature steadily improves.
With Apnicure we believe that we have a product that can treat a portion of OSA patients (about 40-50%) quite well with a device that will be more comfortable, quieter, and overall more acceptable to these patients. We also believe that the effectiveness of the device can be considerably improved in the near future. Thus our plan is to have a highly effective, well-tolerated therapy for OSA.